The One Show will be pedalling into the city on Monday November 10 as Children in Need's rickshaw challenge returns for its fourth fundraising year.
More than £5 million has been raised for the charity, and this year the team are hoping to smash their records.
Beginning at the BBC's Media City near Manchester on Friday November 7, the rickshaw will undertake a 'Salford to Walford' journey across England, finishing live at the EastEnders set during the BBC Children in Need appeal on Friday November 14.
'Team Rickshaw' will be made up of five young people, each supported by projects funded by BBC Children in Need.
They will power the rickshaw for more than 450 miles across England with The One Show presenters on hand to offer support and advice along the way.
Speaking of the challenge Matt Baker said: "We're hoping that Team Rickshaw will raise more than ever, so the pressure is really on for the riders. And of course, to the Great British public, we need your support. It's such a fantastic fundraiser, where people who've benefited from the charity first-hand can really give back, and this year we'll be getting much more of an insight into their own stories, which brings opportunities and challenges of its own. Alex and I have both previously taken on the Rickshaw Challenge so we understand how tough it can be. We will support them every step of the way. "
Alex Jones added: "The Rickshaw Challenge is always tough, but this time it will test the riders both physically and mentally with the addition of the speeches. I can still recall the aches and pain from last year's challenge and can vouch it's a seriously tough journey - even harder without support from the adult riders. This year's team is fantastic, so here's hoping their sheer determination will get them through. Once again we're calling on everyone to show their support and push Team Rickshaw to their most successful year yet!"
David Ramsden, BBC Children in Need Chief Executive, commented: "The One Show Rickshaw Challenge is very special event. At its heart is an amazing team of young people who help to unite the UK in making a real difference for young people."